Steroids and derivatives
Medchemexpress LLC Hydrocortisone sodium phosphate | 6000-74-4 | MFCD00152562 | 99.1% | 486.40 g/mol | C21H29Na2O8P | 25 MG
Hydrocortisone sodium phosphate is the sodium phosphate ester of hydrocortisone, a water-soluble corticosteroid with glucocorticoid anti-inflammatory activity and a short duration of action. It is supplied as a solid research reagent for biochemical and pharmacological studies; consult the safety data sheet for handling and storage.
- Water-soluble sodium phosphate ester of hydrocortisone.
- Provides glucocorticoid anti-inflammatory activity with short duration of action.
- High reported purity supports analytical and biological experiments.
- Suitable for in vitro and in vivo research applications.
- Packaged as a 25 mg solid for convenient small-scale use.
Medchemexpress LLC Dexamethasone phosphate disodium (Standard) | 2392-39-4 | 99.88% | 100 MG
Dexamethasone phosphate (disodium) (Standard) is the analytical standard of Dexamethasone phosphate (disodium). This product is intended for research and analytical applications. Dexamethasone phosphate (Dexamethasone 21-phosphate) disodium is an orally active Glucocorticoid receptor agonist.
- The compound is the grade of analytical standard, which is the reference standard supplied assay.
- Commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Medchemexpress LLC Hydrocortisone acetate | 50-03-3 | 99.14% | 1 G
Hydrocortisone acetate (Hydrocortisone 21-acetate) is a corticosteroid utilized to alleviate swelling, itching, and pain associated with minor skin irritations or hemorrhoids.
- Corticosteroid
- Reduces swelling
- Alleviates itching
- Reduces pain caused by minor skin irritations or hemorrhoids
- Human endogenous metabolite
Medchemexpress LLC Dexamethasone (Standard) | 50-02-2 | MFCD00064136 | 99.0% | 392.46 | 100 MG
Dexamethasone (Standard) | 50-02-2 | MFCD00064136 | 99.0% | 392.46 | 100 MG
Sigma Aldrich Fine Chemicals Biosciences Prednisone Impurity J Phar50MG
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Medchemexpress LLC Hydrocortisone cypionate | 508-99-6 | 486.64 | 5 MG
Hydrocortisone cypionate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It is intended for research use only.
- Down-regulates GR transcript in hCMEC/D3 cells in a dose-dependent manner.
- Supplementation leads to a significant increase in TER across the hCMEC/D3 monolayer.
- Treated dendritic cells (DCs) exhibit decreased expression of MHC II molecules, costimulatory molecule CD86, and DC-specific marker CD83.
- Treated dendritic cells (DCs) show strongly reduced IL-12 secretion.
- Treated dendritic cells (DCs) inhibit IFN-γ production but induce increased release of IL-4.
- Reduces post-ischemic oxidative stress, perfusion pressure, and transudate formation.
- Inhibits post-ischemic shedding of syndecan-1, heparan sulfate, and hyaluronan.
- Inhibits histamine release from mast cells.
Medchemexpress LLC Cortisone acetate | 50-04-4 | 99.9% | 402.48 | 1 G
Cortisone acetate is an oxidized metabolite of Cortisol, a Glucocorticoid, functioning as an immunosuppressant and an anti-inflammatory agent. At high concentrations, it can partially interfere with the binding of Glucocorticoid to the Glucocorticoid-receptor.
- Attenuates apoptosis induced by Cortisol in peripheral-blood mononuclear cells (PBMCs).
- Decreases BCG lesions and tuberculin reactions in rabbits.
- Reduces the number of infiltrating mononuclear cells.
- Reduces caseous necrosis and ulceration.
Medchemexpress LLC Hydrocortisone 17-valerate | 57524-89-7 | 98.0% | 100 MG
Hydrocortisone 17-valerate is a derivative of Hydrocortisone and a corticosteroid ester. It possesses anti-inflammatory effects.
- Has anti-inflammatory effects.
Medchemexpress LLC Dexamethasone 21-acetate | 1177-87-3 | 98.9% | 434.50 | 100 MG
Dexamethasone acetate (Standard) is the analytical standard for Dexamethasone acetate, intended for research and analytical applications. It acts as a glucocorticoid receptor agonist.
- Decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes.
- Effective in controlling COVID-19 infection.
- Inhibits the production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.
- Suitable as a reference standard for assays.
- Commonly used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
Medchemexpress LLC Dexamethasone (Standard) | 50-02-2 | MFCD00064136 | 99.0% | 392.46 | 50 MG
Dexamethasone (Standard) is an analytical standard used in research and analytical applications. It acts as a glucocorticoid receptor agonist, significantly reducing the expression of CD11b, CD18, and CD62L on neutrophils, and CD11b and CD18 on monocytes. It is highly effective in managing COVID-19 infection and inhibits the production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.
- Analytical standard for research and analytical applications
- Glucocorticoid receptor agonist
- Reduces expression of CD11b, CD18, and CD62L on neutrophils, and CD11b and CD18 on monocytes
- Effective in managing COVID-19 infection
- Inhibits production of exosomes containing inflammatory microRNA-155
- Used in qualitative, quantitative, and methodological research experiments (HPLC, GC, MS)
Medchemexpress LLC Hydrocortisone acepo 5mg | 74050-20-7 | 460.56 | C26H36O7 | 5 MG
Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is a potent topical glucocorticoid supplied as a research-grade analytical standard in solid powder and solution forms. It is used for studies of glucocorticoid receptor activity and for research into inflammatory dermatoses. Molecular formula C26H36O7; molecular weight 460.56; CAS 74050-20-7.
- Potent topical glucocorticoid for dermatoses research.
- Provided as powder (solid) and as 10 mM solution in DMSO.
- Intended for research and analytical applications (research use only).
- Target: glucocorticoid receptor; pathway: immunology/inflammation.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Analytical documentation available: COA, HNMR, LCMS.
Selleck Chemical LLC Dexamethasone palmitate S5184-25mg
Dexamethasone palmitate (DXP) a lipophilic prodrug of Dexamethasone (DXM) is a glucocorticoid receptor agonist with a 47-fold lower affinity for the glucocorticoid receptor than DXM Dexamethasone palmitate (DXP) exhibits anti-inflammatory activity
Medchemexpress LLC Hydrocortisone 17-valerate | 57524-89-7 | 98.0% | 50 MG
Hydrocortisone 17-valerate, also known as Cortisol 17-valerate, is a derivative of Hydrocortisone. This corticosteroid ester demonstrates anti-inflammatory effects and is intended for research use only.
- Derivative of hydrocortisone
- Corticosteroid ester
- Exhibits anti-inflammatory effects
- Molecular weight of 446.58
- Chemical formula C26H38O6
- Appears as a white to off-white solid
- Purity of 98.0%
Selleck Chemical LLC Fluocinolone Acetonide 100mg 67-73-2 Flucort-N
Fluocinolone Acetonide (Flucort-N) is a corticosteroid that binds to the cytosolic glucocorticoid receptor. *For Research & Development use only. Product is not intended for drug, household, or human consumption.