Steroids and derivatives
Cayman Chemical 24 25-epoxy Cholesterol 1mg
An oxysterol; inhibits the proliferation of HGC-27 cells at 1 µM, an effect that can be enhanced by knockdown of LXRβ; tumor levels are increased in patients with gastric cancer
Apexbio Technology LLC TRO 19622 22033-87-0 5mg
TRO 19622 (CAS 22033-87-0) also known as Olesoxime is a cholesterol-like small molecule that modulates mitochondrial function contributing to cellular resilience under stress conditions Preclinical studies demonstrate that TRO 19622 attenuates neurodegeneration supports nerve function and facilitates neuroregeneration following traumatic nerve injury in both in vitro and in vivo models This compound is utilized in research exploring neuroprotection and mechanisms underlying neuronal survival with potential applications in models of neurodegenerative diseases and peripheral nerve trauma
Medchemexpress LLC Cinnamoylglycine-2,2-d2 | 1219806-46-8 | 99.4% | C11H9D2NO3 | 5 MG
Cinnamoylglycine-2,2-d2 is a chemical compound with the molecular formula C11H9D2NO3 and CAS number 1219806-46-8. It exhibits a purity of 99.4% by HPLC and appears as a white to off-white solid. This product is intended for research use only.
- Consistent with structure by 1H NMR spectrum
- Isotopic enrichment of 98.96%
- Store as powder at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Skatole-d3 | 111399-60-1 | 134.19 | 10 MG
Skatole-d3 is a deuterium labeled form of Skatole. Skatole is produced by intestinal bacteria and regulates intestinal epithelial cellular functions by activating aryl hydrocarbon receptors and p38. This compound can be used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. It is identified for use as a laboratory chemical and in the manufacture of substances.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Laboratory chemical
- Used in the manufacture of substances
Medchemexpress LLC Eldecalcitol | 104121-92-8 | 99.9% | C30H50O5 | 5 MG
Eldecalcitol (ED-71) is an orally active vitamin D3 analogue that inhibits bone resorption and increases bone mineral density. It also exhibits an anti-tumor effect, inhibits cell proliferation, migration, and induces apoptosis by suppressing GPx-1.
- Orally active vitamin D3 analogue
- Inhibits bone resorption and increases bone mineral density
- Exhibits anti-tumor effects
- Inhibits cell proliferation and migration
- Induces apoptosis by suppressing GPx-1
- Shows no cytotoxicity at 0-50 nM for 24 hours
- Reduces cell death induced by LPS
- Inhibits LPS-induced pyroptosis by activating Nrf2 and its effector molecule HO-1
- Arrests cell cycle at G0/G1 phase
- Stimulates focal bone formation and suppresses bone resorption
![Alkali Scientific Ergocalciferol [Ercalciol Calciferol / Vitamin D2], 10 Grams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000659798.jpg-250.jpg)
Alkali Scientific Ergocalciferol [Ercalciol Calciferol / Vitamin D2], 10 Grams
Ergocalciferol (Vitamin D2, 10g) is a fat-soluble vitamin that plays a crucial role in calcium metabolism, bone health, and immune function. This compound is widely used in nutritional research and clinical applications to study vitamin D deficiency and related diseases. Ergocalciferol is used in research to investigate the role of vitamin D in various biological processes, such as calcium absorption, bone mineralization, and immune response regulation. It is commonly used to treat and prevent vitamin D deficiencies, and it is integral in studies related to osteoporosis, rickets, and autoimmune disorders. This 10g quantity is ideal for laboratory use in vitamin D2 studies and formulations.
Medchemexpress LLC 5,7,4'-Trihydroxy-8-Methylflavanone | 916917-28-7 | 5 MG
5,7,4'-Trihydroxy-8-Methylflavanone, also known as 8-Methyl-naringenine, is a high-purity flavanone compound (99.94%) primarily isolated from *Qualea grandiflora*. This product is intended strictly for research applications and is not for patient use. It is a solid, white to off-white substance with a molecular weight of 286.28 and a chemical formula of C16H14O5. Classified within flavonoids and flavonones, as well as phenols and polyphenols, it can also be sourced from plants like *Ericaceae* and *Rhododendron dauricum Linn.*.
- High purity compound (99.94%)
- Isolated from natural sources such as *Qualea grandiflora*
- Suitable for various research applications
- Identified as a flavanone, phenol, and polyphenol
- Stable for storage at 4°C in sealed conditions, away from moisture
- Can be stored in solvent at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC 1-Methyladenosine-d3 hydriodide | 15763-06-1 | 98.8% | 412.20 | 10 MG
1-Methyladenosine-d3 hydriodide is the deuterium labeled 1-Methyladenosine (HY-113081). 1-Methyladenosine is an RNA modification that can serve as a tumor marker, with elevated levels in the body associated with cancer development. Following 1-methyladenosine methylation, upregulation of PPARδ expression regulates cholesterol metabolism and activates Hedgehog signaling pathway, driving liver tumorigenesis. This product is for research use only and is not sold to patients.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 3(2H)-Pyridazinone, 4,5-dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-6-yl]-5-methyl-d3 | 99.4% | 25 MG
Pimobendan-d3 (UD-CG115-d3) is a deuterium labeled form of Pimobendan, a selective inhibitor of PDE3. It is intended for research use only, not for patient use. Deuterium labeled compounds like Pimobendan-d3 are used as tracers in quantitation during drug development, with deuteration potentially affecting pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Acetamide-2,2,2-d3, N-(4-hydroxyphenyl)- | 60902-28-5 | 100.0% | C8H6D3NO2 | 5 MG
Acetaminophen-d3 is the deuterium labeled form of Acetaminophen (Paracetamol), a widely used antipyretic and analgesic agent. It functions as a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM, and also acts as a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor. This isotope-labeled compound is for research use only.
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Contains stable heavy isotopes for quantitation during drug development
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Thymidine-d3 | 74848-84-3 | 245.25 | 5 MG
Thymidine-d3 | 74848-84-3 | 245.25 | 5 MG
Medchemexpress LLC Dopamine D2 receptor agonist-3 | 1257326-24-1 | 98.3% | 295.81 | C15H22ClN3O | 10 MG
Dopamine D2 receptor agonist-3 is a research compound described as a selective dopamine D2 receptor partial agonist and a dopamine D3 receptor antagonist. It is supplied as a solid powder with documented purity and analytical data for use in in vitro and preclinical receptor pharmacology research.
- High purity of 98.3%.
- Molecular formula C15H22ClN3O and molecular weight 295.81.
- Selective D2 partial agonist and D3 antagonist (pEC50 = 8.3 and <5.5).
- Supplied as a solid powder for research use only.
- Available in multiple sizes, including 10 MG packaging.
- Datasheet and certificate of analysis available.